Title rivals Manchester City and Liverpool collide for the first time this season
The Premier League showdown is happening on the same weekend as the clubs' first meeting last season, when Liverpool won 3-1 at Anfield to open up a nine-point lead over the Citizens.
The Reds could move eight points ahead this time.
Liverpool news
Liverpool expect to welcome back defender Joel Matip, who has missed the last two games through injury.
Thiago Alcantara is will remain sidelined, Reds boss Jurgen Klopp confirmed but Naby Keita is available after returning in Tuesday's Champions League win.
Facts
Liverpool have lost four Premier League fixtures in 2020, the same amount as the previous two years combined.
They have failed to keep a clean sheet in the last 10 league away encounters, conceding 26 goals in total.
They have won only three of their last nine Premier League away matches (D2, L4), following a run of 16 victories in 17 games.
They have conceded 27 Premier League goals since winning the title in June, the joint-most of any top-flight team during that period.
They have conceded 15 goals after seven Premier League games, their most at this stage of a league campaign since 1964-65.
Man City news
Sergio Aguero, Benjamin Mendy and Fernandinho remain out for Pep Guardiola's side.
Facts
Manchester City have won their last three home league games against Liverpool by an aggregate score of 11-1.
They are looking to win consecutive top-flight matches against the Reds for the first time since a run of four victories between 1935 and 1937.
They have won nine of their past 10 Premier League matches against the reigning champions.
They are one short of 100 Premier League home defeats.
Guardiola's eight defeats versus Jurgen Klopp is his worst record against any manager.
Kickoff : 17:30 WAT , 16:30 BST.